Acetolactate Synthase (ALS)

Acetohydroxyacid synthase

Acetohydroxyacid synthase (ALS), a thiamine diphosphate-dependent enzyme, can condense either two pyruvate molecules to form acetolactate for synthesizing Lvaline and L-leucine or pyruvate with 2-ketobutyrate to form acetohydroxybutyrate for synthesizing L-isoleucine. Because the key reaction catalyzed by acetohydroxyacid synthase in the biosynthetic pathways of branched-chain amino acids (valine, leucine, and isoleucine) exists in plants, fungi, archaea, and bacteria, but not in animals, acetohydroxyacid synthase becomes a potential target for developing novel herbicides and antimicrobial compounds.

Acetolactate Synthase (ALS) Inhibitors (10)

Acetolactate Synthase (ALS) Related Products (22):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-100427

Imazamox		99.69%
Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.

HY-B1876

Nicosulfuron	Inhibitor
Nicosulfuron is efficient, harmless, antifungal and selective herbicide belonging to the sulfonylurea family. Nicosulfuron is also a photosynthetic system inhibitor and inhibits acetolactate synthase (ALS) enzyme activity. Nicosulfuron degradation by Plectosphaerella cucumerina AR1 is glucose concentration dependent in planktonic lifestyle. Nicosulfuron enhances the glycolysis pathway and tricarboxylic acid cycle to improve the adaptability of sweet maize. Nicosulfuron reduces the synthesis of branched-chain amino acids (BCAAs), which is proming for maize cultivation.

HY-B1847

Terbuthylazine		≥98.0%
Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide.

HY-119737

Chlorsulfuron		98.47%
Chlorsulfuron blocks the biosynthesis of the amino acids valine and isoleucine in plants. Chlorsulfuron completely alleviates herbicide-induced growth inhibition. The site of action of Chlorsulfuron is the enzyme acetolactate synthase.

HY-B0865

Pyrazosulfuron-ethyl		98.42%
Pyrazosulfuron-ethyl, one of the acetolactate synthase inhibiting herbicides in the sulphonylurea family, has been widely used to control weed growth in commercial cereal, soybean, and vegetable fields.

HY-B1847R

Terbuthylazine (Standard)
Terbuthylazine (Standard) is the analytical standard of Terbuthylazine. This product is intended for research and analytical applications.

HY-B0865R

Pyrazosulfuron-ethyl (Standard)
Pyrazosulfuron-ethyl (Standard) is the analytical standard of Pyrazosulfuron-ethyl. This product is intended for research and analytical applications. Pyrazosulfuron-ethyl, one of the acetolactate synthase inhibiting herbicides in the sulphonylurea family, has been widely used to control weed growth in commercial cereal, soybean, and vegetable fields.

HY-121727

Triafamone	Inhibitor
Triafamone (AE 1887196) is a paddy field pre-emergence and post-emergence sulfonamide herbicide. Triafamone weeds by inhibiting the acetolactate synthase (ALS) enzyme, thereby blocking the biosynthesis of branched-chain amino acids.

HY-B0869A

Bispyribac sodium		99.56%
Bispyribac sodium is a selective, systemic and post emergent herbicide used to eradicate grasses and broad leaf weeds. Bispyribac sodium is also an acetolactate synthase (ALS or known as AHAS) inhibitor.

HY-157816

Fenmezoditiaz	Inhibitor
Fenmezoditiaz exhibits herbicidal activity against various broadleaf and grassy weeds, through inhibition of the acetolactate synthase (ALS).

HY-100427R

Imazamox (Standard)
Imazamox (Standard) is the analytical standard of Imazamox. This product is intended for research and analytical applications. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.

HY-B1876R

Nicosulfuron (Standard)
Nicosulfuron (Standard) is the analytical standard of Nicosulfuron. This product is intended for research and analytical applications. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity.

HY-W422402

Foramsulfuron	Inhibitor
Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids.

HY-158245

Herbicide safener-2
Herbicide safener-2 (Compound III-7) is a herbicide safener with the same pharmacokinetic profile as the safener mefenpyr-diethyl (HY-136376). Herbicide safener-2 competitively binds to the acetolactate synthase (ALS) active site with mesosulfuron-methyl (HY-126987). Herbicide safener-2 protects crops against herbicide injury.

HY-N11854

Brassicanate A sulfoxide	Inhibitor
Brassicanate A sulfoxide has herbicidal activity. Brassicanate A sulfoxide inhibits the biosynthesis of essential amino acids in plants. Brassicanate A sulfoxide binds to dihydroxyacid dehydratase (DHAD), hydroxymethylpyruvate dioxygenase (HPPD), acetolactate synthase (ALS), PYL family proteins and transport inhibitor response 1 (TIR1), and reduces their activity. Brassicanate A sulfoxide can be isolated from Brassica oleracea.

HY-W422402R

Foramsulfuron (Standard)	Inhibitor
Foramsulfuron (Standard) is the analytical standard of Foramsulfuron. This product is intended for research and analytical applications. Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids.

HY-119737R

Chlorsulfuron (Standard)
Chlorsulfuron (Standard) is the analytical standard of Chlorsulfuron. This product is intended for research and analytical applications. Chlorsulfuron blocks the biosynthesis of the amino acids valine and isoleucine in plants. Chlorsulfuron completely alleviates herbicide-induced growth inhibition. The site of action of Chlorsulfuron is the enzyme acetolactate synthase.

HY-126987

Mesosulfuron-methyl	Inhibitor
Mesosulfuron-methyl is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS) and is used in research for post-emergence control of ryegrass and Avena spp. (wild oat) in wheat fields.

HY-126176

Cloransulam-methyl	Inhibitor
Cloransulam-methyl is a triazolopyrimidine sulfonanilide herbicide. Cloransulam-methyl can be used to control broadleaf weeds in soybean by acetolactate synthase (ALS) inhibition.

HY-126176R

Cloransulam-methyl (Standard)	Inhibitor
Cloransulam-methyl (Standard) is the analytical standard of Cloransulam-methyl. This product is intended for research and analytical applications. Cloransulam-methyl is a triazolopyrimidine sulfonanilide herbicide. Cloransulam-methyl can be used to control broadleaf weeds in soybean by acetolactate synthase (ALS) inhibition.

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